Job : 22 Aug 22
Location: Bethesda, Maryland
Education required: PhD
Government and National Laboratory
The Laboratory of Chemical Physics (LCP) conducts innovative and fundamental research in biophysical sciences, including research on fundamental aspects of molecular biophysics, biophysical chemistry and structural biology. LCP research groups are led by a group of outstanding scientists, all of whom are internationally recognized leaders in their fields. LCP group leaders include five members of the National Academy of Sciences, as well as recipients of major awards from the American Physical Society, American Chemical Society, Royal Society of Chemistry, Biophysical Society, the Protein Society, the Welch Foundation and other organizations.
LCP Laboratories are located on the main campus of the National Institutes of Health in Bethesda, Maryland. LCP research is supported by the National Institute of Diabetes, Digestive and Kidney Diseases Intramural Research Program. The LCP group leaders are Philip Anfinrud (ultrafast laser spectroscopy and X-ray diffraction), Ad Bax (methods and applications of biomolecular NMR), Robert Best (molecular simulations and computational methods), Hoi Sung Chung (spectroscopy of multicolor single molecule and imaging), Marius Clore FRS (methods and applications of biomolecular NMR, macromolecular recognition and assembly), William A. Eaton (drug discovery for sickle cell disease), Attila Szabo (theory of single molecule experiments, statistical mechanics ), Rob Tycko (biomolecular solid state NMR, high resolution MRI, cryo-electron microscopy) and Quan Wang (single molecule trapping and spectroscopy with applications to molecular biophysics).
Current research topics at the LCP include: structural studies of proteins and protein assemblies implicated in neurodegenerative and viral diseases; fundamental studies of the folding and interaction mechanisms of proteins and nucleic acids; research on intrinsically disordered proteins of low complexity; development of new experimental methods for single-molecule spectroscopy, time-resolved X-ray diffraction and scattering, and time-resolved magnetic resonance spectroscopy; development of efficient computational methods to simulate protein association and phase separation; and the development of an analytical theory for the interpretation of the results of single molecule experiments. LCP laboratories have state-of-the-art computing equipment and facilities. Additionally, the design and construction of new instrumentation for experiments that go beyond the capabilities of standard equipment is a hallmark of research at the LCP.
Many former LCP postdoctoral fellows are now faculty members at leading research universities in the United States, Canada, Europe, and Asia. Openings for new postdoctoral scientists become available on a regular basis. Applicants with a strong background in the broader biological and physical sciences should contact the individual group leaders, whose contact details are available at https://www.niddk.nih.gov/research-funding/at-niddk/labs-branches/laboratory-chemical-physics .
The NIH and NIDDK are equal opportunity employers. People from diverse backgrounds, including potential candidates from groups currently underrepresented in research staff, are encouraged to apply.